Clinical and ultrasound remission at 48 weeks of upadacitinib in rheumatoid arthritis: real-world results from the Italian multicenter UPARAREMUS study
After 12 months of UPA treatment, a substantial proportion of RA patients achieved combined clinical and US remission, independent of prior bDMARDs use or monotherapy. These findings highlight UPA's ability to induce and maintain deep disease control in real-world practice.
Authors
- Simonetta Salemi (ORCID: https://orcid.org/0000-0003-4754-8092)
- Caterina Baldi (ORCID: https://orcid.org/0000-0002-3070-5568)
- Andrea Picchianti Diamanti (ORCID: https://orcid.org/0000-0002-8552-4641)
- Gian Domenico Sebastiani (ORCID: https://orcid.org/0000-0003-2969-6649)
- Maria Sole Chimenti (ORCID: https://orcid.org/0000-0002-1343-1729)
- Marco Canzoni (ORCID: https://orcid.org/0000-0001-5797-4154)
- Ivan Giovannini (ORCID: https://orcid.org/0000-0002-1110-2518)
- Paolo Falsetti (ORCID: https://orcid.org/0000-0003-2667-4866)
- Donatella Fiore (ORCID: https://orcid.org/0000-0002-0703-7231)
- Valentino Paci (ORCID: https://orcid.org/0000-0002-9466-8460)
- Chiara Scirocco (ORCID: https://orcid.org/0000-0002-0095-300X)
- Annamaria Iagnocco (ORCID: https://orcid.org/0000-0001-5592-724X)
- Alen Zabotti
- Michele Maria Luchetti (ORCID: https://orcid.org/0000-0001-9132-7401)
- Bruno Laganà (ORCID: https://orcid.org/0000-0003-2305-4063)
- Arianna D’Antonio (ORCID: https://orcid.org/0000-0003-1872-5299)
- Giorgio Sesti (ORCID: https://orcid.org/0000-0002-1618-7688)
- Carlo Perricone (ORCID: https://orcid.org/0000-0003-4771-6981)
- Ilaria Anna Bellofatto
- G. Crepaldi
Institutions
- University of Siena (IT)
- University of Rome Tor Vergata (IT)
- Marche Polytechnic University (IT)
- University of Udine (IT)
- University of Perugia (IT)
- Azienda Ospedaliera San Camillo-Forlanini (IT)
- Azienda Ospedaliera Sant'Andrea (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- A. O. Ordine Mauriziano di Torino (IT)
- IRCCS San Camillo Hospital (IT)
- Nini Hospital (LB)
- Ospedale Regina Margherita (IT)
- Carlo Forlanini Hospital (IT)
- University of Turin (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s13075-025-03671-z
- Citations
- 1
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 1.67