Cost-effective, scalable synthesis of cilnidipine nanocrystals for enhanced oral bioavailability and hypertension treatment
CLN-NCs significantly improved <i>in vitro</i> solubility and dissolution, demonstrating a scalable preparation method suitable for industrial translation. This approach offers a promising pathway to enhance CLN's therapeutic efficacy in hypertension management.
Authors
- Mo’tasem M. Alsmadi (ORCID: https://orcid.org/0000-0003-0640-8085)
- Rana Obaidat (ORCID: https://orcid.org/0000-0001-9236-2153)
- Tamara Athamneh
- Aseel Jararweh
Institutions
- University of Jordan (JO)
- University of Science and Technology (YE)
- Jordan University of Science and Technology (JO)
- Water Authority of Jordan (JO)
- Institute of Nanotechnology (GB)
Publication Details
- Journal
- Drug Development and Industrial Pharmacy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1080/03639045.2025.2577754
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.00