Tumor budding predicts lymph node metastasis in squamous cell carcinoma of the lip
Peritumoral tumor budding shows strong predictive potential for lymph node metastasis in LSCC, offering valuable insights for the preoperative evaluation and indication for elective neck dissection.
Authors
- Oliver Vladu (ORCID: https://orcid.org/0009-0003-0735-3060)
- Janik Riese (ORCID: https://orcid.org/0000-0003-0701-060X)
- Danny Jonigk (ORCID: https://orcid.org/0000-0002-5251-2281)
- Claudio Cacchi
- Frank Hölzle (ORCID: https://orcid.org/0000-0002-2298-3517)
- M. Klein (ORCID: https://orcid.org/0000-0003-0569-645X)
- Kai Wermker (ORCID: https://orcid.org/0000-0001-8284-217X)
- Sophie Leypold
Institutions
- Universitätsklinikum Aachen (DE)
- German Center for Lung Research (DE)
- Klinikum Osnabrück (DE)
- German Liver Foundation (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Head & Face Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s13005-025-00553-2
- Primary Topic
- Reconstructive Facial Surgery Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- RWTH Aachen University