Probiotic Weissella cibaria LAB_Weis_Camel_L4 mitigates Escherichia coli-induced enteritis via competitive exclusion and microbiota modulation
<i>Weissella</i> LAB_Weis_Camel_L4 significantly attenuates <i>E. coli</i>-induced intestinal inflammation and promotes mucosal barrier restoration <i>via</i> dual mechanisms involving microbiota modulation and competitive exclusion. Its potent microecological antagonistic activity and capacity to maintain intestinal homeostasis position it as a strong probiotic candidate for antibiotic substitution.
Authors
- Lei Wang (ORCID: https://orcid.org/0000-0003-2433-8842)
- Xueqin Lan
- Mengfei Zhang (ORCID: https://orcid.org/0000-0003-2185-4315)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-1780-0963)
- Yihui Song (ORCID: https://orcid.org/0000-0001-7922-1209)
- Jinxin Xie (ORCID: https://orcid.org/0000-0003-4772-7162)
- Ying Huang (ORCID: https://orcid.org/0000-0003-3569-7576)
- Panpan Tong (ORCID: https://orcid.org/0000-0002-0027-4437)
- Zhanqiang Su
- Wei Zhang (ORCID: https://orcid.org/0000-0001-9459-680X)
- Yongfang Li (ORCID: https://orcid.org/0000-0002-2565-2748)
- Yixin Bai
- Wenjie Jin (ORCID: https://orcid.org/0000-0001-5961-4937)
- Chenyang Shi (ORCID: https://orcid.org/0000-0002-0626-0781)
- Mingyang Geng (ORCID: https://orcid.org/0000-0001-9020-4581)
- Gulina Aishan
Institutions
- Nanjing Agricultural University (CN)
- Xinjiang Agricultural University (CN)
- Research Institute of Animal Husbandry (MN)
- Xinjiang University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1642209
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation
- Xinjiang Agricultural University
- Natural Science Foundation of Xinjiang