Long-term comparative analysis of secukinumab versus TNFα inhibitors in patients with spondyloarthritis: treatment persistence is differentially affected by disease phenotype, obesity and sex
The differential persistence of biologic agents commonly used in SpA has been shown in this real-life prospective study. Should the distinct effects of obesity, sex and specific SpA diagnosis on persistence be confirmed in other cohorts, it could optimize clinical decision-making and improve patient outcomes.
Authors
- Evgenia Emmanouilidou
- Eleni Marolachaki
- George K Bertsias (ORCID: https://orcid.org/0000-0001-5299-1406)
- Argyro Repa (ORCID: https://orcid.org/0000-0002-1044-2449)
- Sofia Pitsigavdaki (ORCID: https://orcid.org/0000-0001-9422-3931)
- Eleni Kalogiannaki (ORCID: https://orcid.org/0009-0004-7930-3545)
- Prodromos I. Sidiropoulos (ORCID: https://orcid.org/0000-0001-9607-0326)
- Irini D. Flouri (ORCID: https://orcid.org/0000-0002-6966-1304)
- Nestor Avgoustidis (ORCID: https://orcid.org/0000-0003-3436-4016)
- Konstantina Kalligianni-Sofikiti
Institutions
- University of Crete (GR)
- Foundation for Research and Technology Hellas (GR)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s13075-025-03664-y
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00