Mycobacterium tuberculosis-induced oligodendrocyte apoptosis promotes astrocyte-mediated cell-in-cell formation and phagocytosis in tuberculous meningitis
Mycobacterium tuberculosis-induced oligodendrocyte apoptosis promotes astrocyte-mediated CIC formation and phagocytosis, suggesting CIC as a novel pathophysiological mechanism in TBM.
Authors
- Qiang Sun (ORCID: https://orcid.org/0000-0003-4766-5512)
- Jie Feng (ORCID: https://orcid.org/0000-0001-7265-9419)
- Jun Zhao (ORCID: https://orcid.org/0000-0001-8903-8205)
- Li Xiao (ORCID: https://orcid.org/0000-0003-0188-4023)
- Zubiao Niu
- Ming Fang (ORCID: https://orcid.org/0000-0002-4103-2063)
- Jiatang Zhang (ORCID: https://orcid.org/0000-0002-9714-0944)
- Feng Qiu (ORCID: https://orcid.org/0000-0003-0137-7718)
- Jianghui Yang
Institutions
- Fudan University (CN)
- Chinese PLA General Hospital (CN)
- Czech Academy of Sciences, Institute of Biotechnology (CZ)
- Beijing Tsinghua Chang Gung Hospital (CN)
- PLA Academy of Military Science (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s12879-025-11934-y
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- General Hospital of People’s Liberation Army