Longitudinal change of idiopathic inflammatory myopathy-associated interstitial lung disease on high-resolution computed tomography, a prospective cohort study
IIM-ILD cases with prior rapid progression will develop chronic fibrotic trajectories with persistent inflammation compared to non-progressive cases. ASS is characterized by sustained inflammatory activity in imaging manifestations, whereas MDA5 + DM shows post-acute fibrotic remodeling following initial injury. Longitudinal GGO emerges as a critical prognostic indicator, demonstrating time-dependent cumulative risk effects.
Authors
- Linfeng Xi (ORCID: https://orcid.org/0000-0001-5702-4159)
- Bing Xie (ORCID: https://orcid.org/0000-0003-2335-5966)
- Min Liu (ORCID: https://orcid.org/0000-0001-7076-5066)
- Jianping Wang (ORCID: https://orcid.org/0000-0002-7141-3473)
- Yinan Hu (ORCID: https://orcid.org/0000-0002-9304-519X)
- Jie Du (ORCID: https://orcid.org/0000-0003-0447-736X)
- Hongyi Wang (ORCID: https://orcid.org/0000-0003-0125-6430)
- Anqi Liu (ORCID: https://orcid.org/0000-0002-9432-4836)
- Yifei Ni
- Yanhong Ren (ORCID: https://orcid.org/0000-0002-1917-9579)
- Jing Geng (ORCID: https://orcid.org/0000-0003-2087-7216)
- Shiyao Wang (ORCID: https://orcid.org/0000-0003-4028-5269)
- Huaping Dai (ORCID: https://orcid.org/0000-0002-0427-1460)
- Yuhui Qiang (ORCID: https://orcid.org/0009-0001-1403-1559)
Institutions
- Academy of Medical Sciences (GB)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- National Clinical Research (US)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s12890-025-03962-w
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00