Mesenchymal stem cells-derived exosomes and Kaempferol improve myelin repair via attenuating inflammation and oxidative stress in a cuprizone-induced demyelination model
These findings suggest that combination therapy with EXOs and KMP improves myelin repair by targeting oxidative stress and neuroinflammation in a CPZ-induced demyelination model.
Authors
- Maryam Ghasemi‐Kasman (ORCID: https://orcid.org/0000-0002-5014-5166)
- Giuseppina Leo (ORCID: https://orcid.org/0000-0001-5972-2268)
- Hamid Askari (ORCID: https://orcid.org/0009-0009-9932-936X)
- Chiara Lucchi (ORCID: https://orcid.org/0000-0003-0965-2948)
- Fatemeh Rabiei (ORCID: https://orcid.org/0009-0002-9122-7018)
- Giuseppe Biagini (ORCID: https://orcid.org/0000-0002-7130-2511)
- Mohammad Javan (ORCID: https://orcid.org/0000-0003-2045-6171)
- Roghayeh Pourbagher (ORCID: https://orcid.org/0000-0002-3812-4581)
Institutions
- University of Modena and Reggio Emilia (IT)
- Tarbiat Modares University (IR)
- Shiraz University of Medical Sciences (IR)
- Babol University of Medical Sciences (IR)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s13287-025-04742-3
- Citations
- 1
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- National Science Foundation
- Iran National Science Foundation
- Babol University of Medical Sciences