Cause-specific mortality in a cohort of paediatric cerebral malaria patients

Multiple different immediate causes of death were identified in children with CM. This may dilute the measured impact of brain-focused therapies aimed at reducing central nervous system injury. Modifications in sample size estimates may need to be made in future clinical trials.

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Publication Details

Journal
Malaria Journal
Published
2025-11-03
DOI
https://doi.org/10.1186/s12936-025-05619-9
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
0.00
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article

Cause-specific mortality in a cohort of paediatric cerebral malaria patients

Christopher A. Moxon, Gretchen L. Birbeck, Terrie E. Taylor, Nicole O’Brien et al.
Malaria Journal
Malaria Research and Control
article

Cause-specific mortality in a cohort of paediatric cerebral malaria patients

Christopher A. Moxon, Gretchen L. Birbeck, Terrie E. Taylor, Nicole O’Brien, Yamikani Chimalizeni, Douglas G. Postels, Karl B. Seydel, Hunter Wynkoop, Ruth Bvalani-Kaunda
article en

Abstract

Multiple different immediate causes of death were identified in children with CM. This may dilute the measured impact of brain-focused therapies aimed at reducing central nervous system injury. Modifications in sample size estimates may need to be made in future clinical trials.

Malaria JournalVol. 24(1)
George Washington University Hospital (US), Nationwide Children's Hospital (US), Children's National (US), Kamuzu Central Hospital (MW), University Teaching Hospital (ZM), Wellcome Centre for Molecular Parasitology (GB), Kamuzu University of Health Sciences (MW), University of Rochester (US), Michigan State University (US)
Openalex Percentile: Top 58%
Malaria Research and Control
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