Prognostic Value of Exercise Right Ventricular–Pulmonary Arterial Coupling in Primary Mitral Regurgitation

Exercise right ventricular-pulmonary arterial coupling, particularly intermediate exTAPSE/sPAP, is a robust and feasible measure independently associated with adverse outcomes, and provides prognostic information beyond resting variables and cardiorespiratory fitness, potentially refining risk stratification and guiding management in patients with primary mitral regurgitation.

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Publication Details

Journal
Circulation
Published
2025-11-03
DOI
https://doi.org/10.1161/circulationaha.125.073778
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Prognostic Value of Exercise Right Ventricular–Pulmonary Arterial Coupling in Primary Mitral Regurgitation

Philippe Debonnaire, Wouter L’Hoyes, Stefano Masi, Maarten Falter et al.
Circulation
Pulmonary Hypertension Research and Treatments
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Prognostic Value of Exercise Right Ventricular–Pulmonary Arterial Coupling in Primary Mitral Regurgitation

Philippe Debonnaire, Wouter L’Hoyes, Stefano Masi, Maarten Falter, Steven Droogmans, Maurício Milani, Youri Bekhuis, Jan Verwerft, Lavinia Del Punta, Giosuè Falcetta, Marco De Carlo, Lieven Herbots, Philippe B. Bertrand, Bernard Cosyns, Sarah Hoedemakers, Rūta Jasaitytė, Stefano Taddei, Guido Claessen, Sebastiaan Dhont, Matteo Mazzola, Nicolò De Biase, Sara Ferreira, Nicola Riccardo Pugliese, Annemie Jacobs
article en

Abstract

Exercise right ventricular-pulmonary arterial coupling, particularly intermediate exTAPSE/sPAP, is a robust and feasible measure independently associated with adverse outcomes, and provides prognostic information beyond resting variables and cardiorespiratory fitness, potentially refining risk stratification and guiding management in patients with primary mitral regurgitation.

CirculationVol. 152(23)
University of Pisa (IT), Jessa Hospital (BE), Technologies pour la Santé (FR), AZ Sint-Jan (BE), Universitair Ziekenhuis Brussel (BE), Imelda Hospital (BE), Ziekenhuis Oost-Limburg (BE), Azienda Ospedaliera Universitaria Pisana (IT), Hasselt University (BE), KU Leuven (BE)
Openalex Percentile: Top 54%
Pulmonary Hypertension Research and Treatments
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