Elevated NUF2 and CD52 expression predict platinum-based chemoresistance and poor prognosis in non-small cell lung cancer

High expression of NUF2 and CD52 is closely linked to platinum resistance and aggressive tumor behavior in NSCLC, and serves as an independent predictor of adverse outcomes. These markers may hold potential as prognostic indicators and therapeutic targets in chemoresistant NSCLC. These findings, while promising, are based on a single-center retrospective cohort and should be validated in larger, independent studies to confirm their clinical utility.