Fragile X mental retardation 1 gene FMR1 promotes proliferation, migration, and invasion of gastric cancer cells via c-MYC
Our findings demonstrate that FMR1 promotes gastric cancer cell proliferation, migration, and invasion through c-MYC signaling, suggesting that FMR1 may serve as a potential prognostic biomarker and therapeutic target for gastric cancer.
Authors
- Nan Hu (ORCID: https://orcid.org/0000-0003-1528-5726)
- Meirong Liang (ORCID: https://orcid.org/0000-0002-4159-5026)
- Kangjie Zhou (ORCID: https://orcid.org/0000-0002-2090-2920)
- Fenglei Wu (ORCID: https://orcid.org/0000-0002-0825-086X)
- Yidong Hong
- Jingzhou Zhang (ORCID: https://orcid.org/0000-0002-8803-2861)
- Luming Zhao
- Chenxi Mao
- Yiqian Han
Institutions
- Xuzhou Medical College (CN)
- Lianyungang Oriental Hospital (CN)
- The First People’s Hospital of Lianyungang (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s12967-025-07140-8
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Lianyungang Science and Technology Bureau