Clinical relevance of perioperative changes in circulating tumor cells in resectable colorectal cancer
Preoperative CTC positivity was significantly associated with an increased risk of lymph node metastasis, supporting its potential role in assessing tumor aggressiveness. In addition, postoperative CTC positivity showed an exploratory association with shorter disease-free survival, suggesting a possible prognostic value that warrants further investigation.
Authors
- Dan Wu (ORCID: https://orcid.org/0000-0002-1302-463X)
- Qingyang Feng (ORCID: https://orcid.org/0009-0005-3454-5206)
- Fangmin Zhou (ORCID: https://orcid.org/0000-0003-2604-3917)
- Xiao Wei Sun (ORCID: https://orcid.org/0000-0002-2840-1880)
- Junjia Zhu (ORCID: https://orcid.org/0000-0003-1311-3752)
- Nan Xiang (ORCID: https://orcid.org/0000-0002-2283-1521)
- Ni Chen (ORCID: https://orcid.org/0000-0002-0628-0723)
- Ya Qin (ORCID: https://orcid.org/0000-0002-9338-1345)
Institutions
- Jiangyin People's Hospital (CN)
- Southeast University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s12885-025-15087-8
- Citations
- 1
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Natural Science Foundation of China