Changes in emotional dysregulation profile among offspring of parents with bipolar disorder: a family-based intervention pilot study
Offspring of parents with bipolar disorder (OBD) are at increased risk for mood and behavioral disorders, with emotional dysregulation being an early marker. This pilot study aimed to evaluate the effect of a family-focused intervention on emotional dysregulation in OBD, hypothesizing a significant reduction in CBCL Emotional Dysregulation Profile scores over 12 months. Twenty-five OBD aged 6-16 years participated in a four-session psychoeducational program. Significant reductions were observed in CBCL emotional dysregulation scores suggesting that a brief family-focused program may reduce dysregulation and improve functioning in OBD. TRIAL REGISTRATION NUMBER: Clinicaltrials.gov. ID NCT03299140. Registered on the 17th September, 2017.
Authors
- Nathalie Franc
- Hala Kerbage (ORCID: https://orcid.org/0000-0002-5509-6471)
- Diane Purper‐Ouakil (ORCID: https://orcid.org/0000-0003-0454-1579)
- Erica Fongaro (ORCID: https://orcid.org/0000-0001-5113-1244)
- Émilie Olié (ORCID: https://orcid.org/0000-0001-6684-8141)
- Florence Pupier
- M. Soler
- Virginie Maurice
- Marie‐Christine Picot
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Université de Montpellier (FR)
- Neuropsychiatrie : Recherche Epidemiologique et Clinique (FR)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Hôpital Lapeyronie (FR)
- Hôpital Saint Eloi (FR)
- Institut de Génomique Fonctionnelle (FR)
Publication Details
- Journal
- International Journal of Bipolar Disorders
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1186/s40345-025-00398-3
- Primary Topic
- Maternal Mental Health During Pregnancy and Postpartum
- Type
- article
- Field-Weighted Citation Impact
- 0.00