Neutrophilic-dominant phenotype during exacerbations predicts adverse hospital outcomes in asthma-bronchiectasis overlap syndrome
ABOS exacerbations exhibit distinct inflammatory phenotypes. The neutrophilic-lymphopenic phenotype strongly predicts in-hospital adverse outcomes, highlighting its potential for acute risk stratification in hospitalized patients.
Authors
- Hong Ping Zhang (ORCID: https://orcid.org/0000-0003-4312-0099)
- Deying Kang (ORCID: https://orcid.org/0000-0003-1488-7047)
- L. Zhang (ORCID: https://orcid.org/0000-0002-8312-7765)
- Yulai Yuan
- Min Feng (ORCID: https://orcid.org/0000-0001-9801-650X)
- Lei Liu (ORCID: https://orcid.org/0000-0002-0500-6239)
- Gang Wang (ORCID: https://orcid.org/0000-0001-8898-0012)
- Gang Wang (ORCID: https://orcid.org/0000-0002-5048-6606)
- Ying Liu (ORCID: https://orcid.org/0000-0002-9581-3586)
- Yin Li (ORCID: https://orcid.org/0000-0002-4754-2814)
- Qin Wang
- Shuwen Zhang (ORCID: https://orcid.org/0000-0003-3555-6677)
- Lingyun Lu (ORCID: https://orcid.org/0000-0003-3629-1420)
- Lishan Yuan
- Chongyang Zhao
- Xin Zhang (ORCID: https://orcid.org/0000-0003-0047-3134)
Institutions
- University of Technology Sydney (AU)
- Sichuan University (CN)
- Woolcock Institute of Medical Research (AU)
- China-Japan Friendship Hospital (CN)
- Karolinska Institutet (SE)
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- West China Hospital of Sichuan University (CN)
- Stockholm South General Hospital (SE)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1080/02770903.2025.2577639
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00