An accessible approach to density estimation neural networks with data preprocessing

Density estimation neural networks (DENNs) represent a form of artificial neural network designed to provide an efficient approach to the Bayesian estimation of a probability density on a model parameter space, conditioned on an empirical observation of the underlying system. Despite their efficiency and potential, DENNs remain underutilized for parameter estimation in mathematical modeling. In this work, we aim to boost the accessibility of the DENN approach by providing a user-friendly introduction and code that makes it easy for users to harness existing, cutting-edge DENN software. Furthermore, we insert an easily-implemented preliminary data simulation step that reduces the computational demands of the approach and empirically demonstrates that it maintains the accuracy of parameter estimation for a stochastic oscillator model.

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Publication Details

Journal
Mathematical Biosciences & Engineering
Published
2025-01-01
DOI
https://doi.org/10.3934/mbe.2025116
Primary Topic
Neural Networks and Applications
Type
article
Field-Weighted Citation Impact
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article

An accessible approach to density estimation neural networks with data preprocessing

Jonathan E. Rubin, Bing Hou
Mathematical Biosciences & Engineering
Neural Networks and Applications
article

An accessible approach to density estimation neural networks with data preprocessing

Jonathan E. Rubin, Bing Hou
article en

Abstract

Density estimation neural networks (DENNs) represent a form of artificial neural network designed to provide an efficient approach to the Bayesian estimation of a probability density on a model parameter space, conditioned on an empirical observation of the underlying system. Despite their efficiency and potential, DENNs remain underutilized for parameter estimation in mathematical modeling. In this work, we aim to boost the accessibility of the DENN approach by providing a user-friendly introduction and code that makes it easy for users to harness existing, cutting-edge DENN software. Furthermore, we insert an easily-implemented preliminary data simulation step that reduces the computational demands of the approach and empirically demonstrates that it maintains the accuracy of parameter estimation for a stochastic oscillator model.

Mathematical Biosciences & EngineeringVol. 22(12)
University of Pittsburgh (US), Columbia University (US)
Openalex Percentile: Top 83%
Neural Networks and Applications
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