Giant Cell Aortitis and Tuberculosis: Coincidence or a Causal Link?

Aortitis is a rare inflammatory condition with diverse etiologies. Tuberculosis, though infrequently involved, may coexist with giant cell arteritis (GCA), sharing similar clinical features that complicate diagnosis. Their association is exceptionally rare, presenting a significant diagnostic challenge for clinicians. A 61-year-old man with no prior medical history presented with systemic and inflammatory symptoms, revealing diffuse aortitis associated with both tuberculosis and GCA, the latter confirmed by temporal artery biopsy. The rare coexistence of tuberculous aortitis and GCA poses a diagnostic challenge, requiring thorough analysis of clinical, biological, histological, and progressive findings.

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Publication Details

Journal
Cureus
Published
2025-11-02
DOI
https://doi.org/10.7759/cureus.95972
Primary Topic
Vasculitis and related conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Giant Cell Aortitis and Tuberculosis: Coincidence or a Causal Link?

Nacima Djennane, Souad Bellaifa, Said Taharboucht, Asma Azoug et al.
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Vasculitis and related conditions
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Giant Cell Aortitis and Tuberculosis: Coincidence or a Causal Link?

Nacima Djennane, Souad Bellaifa, Said Taharboucht, Asma Azoug, El Djouher Saidoun
article en

Abstract

Aortitis is a rare inflammatory condition with diverse etiologies. Tuberculosis, though infrequently involved, may coexist with giant cell arteritis (GCA), sharing similar clinical features that complicate diagnosis. Their association is exceptionally rare, presenting a significant diagnostic challenge for clinicians. A 61-year-old man with no prior medical history presented with systemic and inflammatory symptoms, revealing diffuse aortitis associated with both tuberculosis and GCA, the latter confirmed by temporal artery biopsy. The rare coexistence of tuberculous aortitis and GCA poses a diagnostic challenge, requiring thorough analysis of clinical, biological, histological, and progressive findings.

CureusVol. 17(11)
University of Algiers Benyoucef Benkhedda (DZ), Centre Hospitalo-Universitaire Bab El Oued (DZ)
Openalex Percentile: Top 54%
Vasculitis and related conditions
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