Yiqi Huoxue recipe ameliorates diabetic nephropathy by mediating VAPB–PTPIP51 complex to activate autophagy and regulate MAM contact
YHR may protect kidneys in DN by regulating the MAM complex VAPB-PTPIP51 to trigger autophagy, providing insights into TCM's clinical application and DN drug development.
Authors
- Guan Yang (ORCID: https://orcid.org/0000-0002-4026-6976)
- M Y Wang (ORCID: https://orcid.org/0009-0001-0150-2753)
- Linghao Dai (ORCID: https://orcid.org/0009-0007-4624-9994)
- Haowei Liang
- Hui Wang (ORCID: https://orcid.org/0000-0003-0108-8254)
- Bo Wang (ORCID: https://orcid.org/0000-0002-7046-2759)
- Zhongyan Du
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinhua Academy of Agricultural Sciences (CN)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3389/fnut.2025.1634555
- Citations
- 3
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Natural Science Foundation of China