Neuroimaging and molecular mechanism of action of Cang-ai volatile oil in the treatment of vascular cognitive impairment
This study demonstrates that CAVO therapy reduces inflammatory responses in brain regions of VCI rats, decreases apoptosis and necrosis, protects neurons in affected areas, and simultaneously enhances functional connectivity strength between brain regions in VCI rats, thereby exerting a cognitive-improving effect on VCI.
Authors
- Bojun Chen (ORCID: https://orcid.org/0000-0002-0567-4245)
- Jiaojian Wang (ORCID: https://orcid.org/0000-0002-0421-5709)
- Lei Wang (ORCID: https://orcid.org/0000-0002-3950-0171)
- Wei Li (ORCID: https://orcid.org/0000-0002-1256-4423)
- Lei Xiong (ORCID: https://orcid.org/0000-0003-3799-7679)
- Fabao Gao (ORCID: https://orcid.org/0009-0000-6143-8127)
- Boshen Liang
Institutions
- Kunming University of Science and Technology (CN)
- Guangzhou University of Chinese Medicine (CN)
- Yunnan University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3389/fnins.2025.1688649
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Kunming Medical University
- Sichuan University
- Yunnan University
- West China Hospital, Sichuan University