Identification of anoikis-related genes and immune infiltration characteristics in Sjögren’s syndrome based on machine learning

This study substantiates the significant involvement of anoikis in SS and suggests that <i>MAPK3, IL15, S100A9, IFI27</i>, and <i>CXCL10</i> may serve as critical biomarkers in the inflammatory progression of SS. These genes likely mediate their effects by influencing immune cell infiltration, participating in immune regulation, and modulating inflammatory responses. Our findings offer new insights into drug selection and immunotherapeutic strategies for SS.