An mRNA-based FimH nanoparticle vaccine against uropathogenic Escherichia coli is highly immunogenic in rodents
The mRNA vaccine FimH<sub>DG</sub>-Ferritin with N1mΨ-modified nucleosides is a promising candidate for further development as a vaccine against UPEC.
Authors
- Susanne Rauch (ORCID: https://orcid.org/0009-0008-4587-5384)
- Roberto Rosini
- Alfredo Pezzicoli
- Roberto Adamo (ORCID: https://orcid.org/0000-0001-5228-6088)
- Sandro Roier
- Benjamin Petsch (ORCID: https://orcid.org/0000-0001-7431-0683)
- Maria Scarselli (ORCID: https://orcid.org/0000-0002-6261-1160)
- Edith Jasny
Institutions
- CureVac (Germany) (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1668937
- Citations
- 1
- Primary Topic
- Escherichia coli research studies
- Type
- article
- Field-Weighted Citation Impact
- 1.80
Funders
- Syddansk Universitet