Cyp2e1 deletion in mice increases sensitivity to ethanol‐induced motor impairment and escalation of drinking behavior in the chronic intermittent ethanol model
This study reveals an important role for Cyp2e1 in ethanol-related behaviors and highlights a need to better understand the effects of ethanol and its metabolites in mediating ethanol drinking and sensitivity.
Authors
- Howard C. Becker (ORCID: https://orcid.org/0000-0001-8042-6957)
- Jessica H. Hartman (ORCID: https://orcid.org/0000-0002-9032-7191)
- Patrick J. Mulholland (ORCID: https://orcid.org/0000-0003-0780-5971)
- Joe Ryan Delaney (ORCID: https://orcid.org/0000-0002-8978-5961)
- Kelly R. Misare
- Marcelo F. Lopez (ORCID: https://orcid.org/0000-0001-5885-7371)
- H. Gustavsson Gonzalez (ORCID: https://orcid.org/0000-0002-2925-8457)
- Kate E. Glorioso (ORCID: https://orcid.org/0009-0002-6662-3238)
Institutions
- Medical University of South Carolina (US)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2025-11-02
- DOI
- https://doi.org/10.1111/acer.70188
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health