The Use of Allografts in Ankle Injuries

Ankle sprains can damage the lateral ankle ligament complex, resulting in lateral ankle instability or intra-articular cartilage damage, like osteochondral defects (OCD). Both ankle instability and OCD can lead to ankle osteoarthritis, resulting in substantial disability and negatively impacting patients' quality of life. Treating these lesions could be challenging, and various surgical procedures have been described in the literature, including allografts, which have gained popularity and shown promising results in the last few years. The main advantages of allografts include the absence of donor site morbidity, the single-stage procedure, the reduced surgical time, and the alleviation of the possible iatrogenic weakening of the graft. In addition, in cases of OCD, allografts can effectively replace the subchondral bone and are suitable for irregularly shaped defects. Recent literature has demonstrated that allografts significantly improve functional scores and patient-reported outcomes measures and, therefore, are a valuable option to cope with these ankle pathologies.

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Publication Details

Journal
Sports Medicine and Arthroscopy Review
Published
2025-04-29
DOI
https://doi.org/10.1097/jsa.0000000000000435
Primary Topic
Foot and Ankle Surgery
Type
article
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article

The Use of Allografts in Ankle Injuries

René Verdonk, Efthymios Iliopoulos, Konstantinos G. Makiev, Theofylaktos Kyriakidis et al.
Sports Medicine and Arthroscopy Review
Foot and Ankle Surgery
article

The Use of Allografts in Ankle Injuries

René Verdonk, Efthymios Iliopoulos, Konstantinos G. Makiev, Theofylaktos Kyriakidis, Vasileios Davitis
article en

Abstract

Ankle sprains can damage the lateral ankle ligament complex, resulting in lateral ankle instability or intra-articular cartilage damage, like osteochondral defects (OCD). Both ankle instability and OCD can lead to ankle osteoarthritis, resulting in substantial disability and negatively impacting patients' quality of life. Treating these lesions could be challenging, and various surgical procedures have been described in the literature, including allografts, which have gained popularity and shown promising results in the last few years. The main advantages of allografts include the absence of donor site morbidity, the single-stage procedure, the reduced surgical time, and the alleviation of the possible iatrogenic weakening of the graft. In addition, in cases of OCD, allografts can effectively replace the subchondral bone and are suitable for irregularly shaped defects. Recent literature has demonstrated that allografts significantly improve functional scores and patient-reported outcomes measures and, therefore, are a valuable option to cope with these ankle pathologies.

Sports Medicine and Arthroscopy ReviewVol. 33(4)
Democritus University of Thrace (GR), Aristotle University of Thessaloniki (GR), Interbalkan Medical Center (GR), Erasmus Hospital (BE)
Openalex Percentile: Top 58%
Foot and Ankle Surgery
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The Use of Allografts in Ankle Injuries — René Verdonk, Efthymios Iliopoulos, et al. · Sports Medicine and Arthroscopy Review (2025) | TGRS Research Map | TGRS