Association between oral JAK-1 inhibitors and infection risks in atopic dermatitis: a retrospective analysis of the FAERS database
This study confirms established infection risks of JAK-1 inhibitors in AD (particularly herpes zoster) and identifies novel potential safety signals (sepsis, appendicitis, and septic shock). These findings provide real-world insights into the risk of infections associated with JAK inhibitors.
Authors
- Zhanglei Mu (ORCID: https://orcid.org/0000-0003-3470-608X)
- Z. Q. Tang (ORCID: https://orcid.org/0000-0002-4908-6007)
- Xiaojie Wang (ORCID: https://orcid.org/0000-0002-2616-3196)
- Yan Zhao (ORCID: https://orcid.org/0009-0005-4105-2696)
Institutions
- Peking University (CN)
- Peking University People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.3389/fmed.2025.1694688
- Citations
- 3
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.01
Funders
- Peking University
- Peking University People's Hospital