Two‐tier screening approach for liver fibrosis stratification in outpatients with type 2 diabetes mellitus: A multicenter cross‐sectional study
MASLD and significant liver fibrosis are common in older patients with T2DM. Fibrosis risk stratification using FIB-4, followed by VCTE, is a good strategy in real-world settings. However, relying solely on FIB-4 may fail to identify some patients with advanced disease, particularly those with increased body weight and elevated serum aminotransferase levels.
Authors
- Nicoletta Rolli
- Valeria Guglielmi (ORCID: https://orcid.org/0000-0002-6912-7814)
- Alessandro Mantovani (ORCID: https://orcid.org/0000-0002-7271-6329)
- Paolo Sbraccia (ORCID: https://orcid.org/0000-0001-9634-1501)
- Dario Messetti
- Riccardo Morandin (ORCID: https://orcid.org/0000-0003-2511-041X)
- Giovanni Targher (ORCID: https://orcid.org/0000-0002-4325-3900)
- Mirko Zoncapè (ORCID: https://orcid.org/0000-0002-2391-1689)
- Frida Leonetti (ORCID: https://orcid.org/0000-0002-5606-8448)
- Andrea Dalbeni (ORCID: https://orcid.org/0000-0003-0402-4176)
- Maria Giovanna Lando
- Rosa Lombardi (ORCID: https://orcid.org/0000-0003-0470-231X)
- Veronica Fiorio
- Marta Di Forti (ORCID: https://orcid.org/0000-0002-3218-6925)
- Danila Capoccia
- Maria Eugenia Parrotta
- Anna Ludovica Fracanzani
- Ilaria Milani (ORCID: https://orcid.org/0009-0004-0120-4731)
Institutions
- University of Verona (IT)
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Ospedale Sacro Cuore Don Calabria (IT)
- Policlinico Tor Vergata (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-11-02
- DOI
- https://doi.org/10.1111/dom.70245
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71