Metformin Inhibits the Growth of Hypopharyngeal Squamous Cell Carcinoma of Fadu Cell and Down-Regulates LncAROD to Improve Prognosis

This finding presents a novel approach to the clinical management of HSCC, indicating that metformin influences various processes related to the growth and progression of HSCC. Specifically, it reduces lncAROD expression and inhibits tumor progression, suggesting that lncAROD may serve as a valuable biomarker for evaluating the prognosis of HSCC.

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Publication Details

Journal
Anti-Cancer Agents in Medicinal Chemistry
Published
2025-10-29
DOI
https://doi.org/10.2174/0118715206427268251006112304
Primary Topic
Peroxisome Proliferator-Activated Receptors
Type
article
Field-Weighted Citation Impact
0.00
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article

Metformin Inhibits the Growth of Hypopharyngeal Squamous Cell Carcinoma of Fadu Cell and Down-Regulates LncAROD to Improve Prognosis

Meiyu Liu, Fang Liu, Desheng Wang
Anti-Cancer Agents in Medicinal Chemistry
Peroxisome Proliferator-Activated Receptors
article

Metformin Inhibits the Growth of Hypopharyngeal Squamous Cell Carcinoma of Fadu Cell and Down-Regulates LncAROD to Improve Prognosis

Meiyu Liu, Fang Liu, Desheng Wang
article en

Abstract

This finding presents a novel approach to the clinical management of HSCC, indicating that metformin influences various processes related to the growth and progression of HSCC. Specifically, it reduces lncAROD expression and inhibits tumor progression, suggesting that lncAROD may serve as a valuable biomarker for evaluating the prognosis of HSCC.

Anti-Cancer Agents in Medicinal ChemistryVol. 26
Fujian Medical University (CN), Gannan Medical University (CN), First Affiliated Hospital of Gannan Medical University (CN), Union Hospital (CN)
Openalex Percentile: Top 72%
Peroxisome Proliferator-Activated Receptors
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