Foxp3 <sup>+</sup> Tregs Promote M2 Macrophage Polarization via Sirt1-ERK1/2- STAT3 Pathway in Ovarian Cancer Progression
Foxp3⁺ Tregs drive immunosuppressive macrophage polarization and ovarian cancer progression, highlighting Foxp3 as a potential therapeutic target for EOC treatment.
Authors
- Zhaohui Xu (ORCID: https://orcid.org/0000-0003-0645-1737)
- Yunfeng Jin (ORCID: https://orcid.org/0000-0001-5544-5048)
- Yi Yang (ORCID: https://orcid.org/0000-0001-9898-0366)
- Hui Chen (ORCID: https://orcid.org/0000-0002-5423-6989)
- Li Li (ORCID: https://orcid.org/0000-0002-4602-8979)
- Bo Guo (ORCID: https://orcid.org/0000-0001-8986-5470)
- Ning Liang (ORCID: https://orcid.org/0000-0002-6795-2255)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Current Gene Therapy
- Published
- 2025-11-03
- DOI
- https://doi.org/10.2174/0115665232417125251021114250
- Citations
- 4
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.19