The Hidden Culprit: Abdominal Tuberculosis Masquerading as Ovarian Cancer in a 22-Year-Old Woman

Abdominal tuberculosis (TB) is a rare extrapulmonary manifestation of TB in Europe. It may resemble ovarian cancer, especially when ascites, an adnexal mass, and elevated CA-125 levels are present. This case report aims to underline the significance of considering abdominal TB as a differential diagnosis when evaluating ascites with an adnexal mass. The presence of an adnexal mass and ascites should prompt consideration of a TB origin among the possible causes. This case highlights a significant diagnostic challenge, with delays in both diagnosis and management. The patient was evaluated across six specialities (Accident & Emergency, Acute Medicine, Gynaecology, Gynae-Oncology, Infectious Diseases, and Respiratory Medicine), illustrating the complexity and multisystem involvement that contributed to the prolonged diagnostic pathway. Diagnosis of abdominal TB can be challenging and time-consuming. Imaging and tumour markers alone are insufficient. Definitive diagnosis often requires histopathological examination and PCR testing to confirm the presence and nature of the disease.

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Publication Details

Journal
Cureus
Published
2025-11-02
DOI
https://doi.org/10.7759/cureus.95959
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
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article

The Hidden Culprit: Abdominal Tuberculosis Masquerading as Ovarian Cancer in a 22-Year-Old Woman

Zaid Aldin, Safwaan Adam, S. A. Noreldeen, Amira A. Hassan et al.
Cureus
Diagnosis and treatment of tuberculosis
article

The Hidden Culprit: Abdominal Tuberculosis Masquerading as Ovarian Cancer in a 22-Year-Old Woman

Zaid Aldin, Safwaan Adam, S. A. Noreldeen, Amira A. Hassan, Saimah Arif
article en

Abstract

Abdominal tuberculosis (TB) is a rare extrapulmonary manifestation of TB in Europe. It may resemble ovarian cancer, especially when ascites, an adnexal mass, and elevated CA-125 levels are present. This case report aims to underline the significance of considering abdominal TB as a differential diagnosis when evaluating ascites with an adnexal mass. The presence of an adnexal mass and ascites should prompt consideration of a TB origin among the possible causes. This case highlights a significant diagnostic challenge, with delays in both diagnosis and management. The patient was evaluated across six specialities (Accident & Emergency, Acute Medicine, Gynaecology, Gynae-Oncology, Infectious Diseases, and Respiratory Medicine), illustrating the complexity and multisystem involvement that contributed to the prolonged diagnostic pathway. Diagnosis of abdominal TB can be challenging and time-consuming. Imaging and tumour markers alone are insufficient. Definitive diagnosis often requires histopathological examination and PCR testing to confirm the presence and nature of the disease.

CureusVol. 17(11)
Princess Alexandra Hospital NHS Trust (GB), Ipswich Hospital (AU), Princess Alexandra Hospital (GB), Ipswich Hospital (GB)
Openalex Percentile: Top 50%
Diagnosis and treatment of tuberculosis
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