Development of eosinophilic esophagitis during wheat oral immunotherapy in children: a retrospective cohort analysis

EoE occurred in 10% of children during wheat OIT, mainly in the up-dosing phase. While symptoms resolved with treatment and cessation, distinguishing transient OIT-induced eosinophilia from persistent EoE remains critical. Prospective studies with pre- and post-OIT endoscopy are needed to guide monitoring and management.

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Publication Details

Journal
Immunotherapy
Published
2025-10-13
DOI
https://doi.org/10.1080/1750743x.2025.2578444
Primary Topic
Eosinophilic Esophagitis
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of eosinophilic esophagitis during wheat oral immunotherapy in children: a retrospective cohort analysis

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Eosinophilic Esophagitis
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Development of eosinophilic esophagitis during wheat oral immunotherapy in children: a retrospective cohort analysis

Morteza Fallahpour, Ali Pourvali, Amin Tajerian, Maryam Zamanian, Mohammad Nabavi, Mohammad Hasan Bemanian, Javad Nazari
article en

Abstract

EoE occurred in 10% of children during wheat OIT, mainly in the up-dosing phase. While symptoms resolved with treatment and cessation, distinguishing transient OIT-induced eosinophilia from persistent EoE remains critical. Prospective studies with pre- and post-OIT endoscopy are needed to guide monitoring and management.

ImmunotherapyVol. 17(15)
Arak University of Medical Sciences (IR), Iran University of Medical Sciences (IR)
Openalex Percentile: Top 50%
Eosinophilic Esophagitis
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