Local IgE is a superior biomarker than serum IgE for nasal type 2 inflammation in house dust mites sensitized allergic rhinitis
Local sIgE demonstrates high diagnostic accuracy for HDM-sensitized AR and better reflects local Th2-driven inflammation. The nonlinear local-serum sIgE relationship advocates dual-compartment profiling, advancing precision diagnostics in AR.
Authors
- Yanhua Song (ORCID: https://orcid.org/0000-0003-4094-3946)
- Lin Xi (ORCID: https://orcid.org/0000-0003-0028-6873)
- Y Zhang (ORCID: https://orcid.org/0000-0001-7646-1581)
- Chong Wang (ORCID: https://orcid.org/0000-0002-5804-9750)
- J Li (ORCID: https://orcid.org/0000-0001-5197-193X)
- Xiaolei Zhang (ORCID: https://orcid.org/0000-0003-0117-7599)
- Zheng Zhang (ORCID: https://orcid.org/0009-0003-2498-9693)
- Lin Zhang (ORCID: https://orcid.org/0000-0002-2064-8440)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- Rhinology Journal
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4193/rhin25.381
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China