The prognostic impact of blood vessel invasion in infiltrative papillary thyroid carcinoma: a retrospective case–control study
Using CD31 and D2-40 as gold standard ancillary tools, we established reliable histologic criteria to differentiate BVI from LI. Extensive BVI is an independent adverse prognostic factor in infiltrative BRAF V600E-like PTC and should therefore be considered in initial risk stratification for infiltrative PTC.
Authors
- Robert Michael Tuttle (ORCID: https://orcid.org/0000-0001-9899-9702)
- Bin Xu (ORCID: https://orcid.org/0000-0003-4638-9835)
- Ashok R. Shaha (ORCID: https://orcid.org/0000-0001-7478-9436)
- Ronald Ghossein (ORCID: https://orcid.org/0000-0003-2802-8489)
- Dibisha Roy (ORCID: https://orcid.org/0009-0009-8612-1711)
Institutions
- Memorial Sloan Kettering Cancer Center (US)
Publication Details
- Journal
- Histopathology
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1111/his.70032
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00