Comparative study of some BAS groups of the hydrophilic fraction of coriander fruits (Coriandrum sativum L.) and fennel fruits (Foeniculum vulgare Mill.)

Introduction. The fruits of coriander ( Coriandrum sativum L.) and fennel ( Foeniculum vulgare Mill.), of the celery family ( Apiaceae ), are approved for medical use in the form of aqueous extracts, while the standardization of raw materials is carried out according to the content of essential oil and its component composition, and the hydrophilic fraction of biologically active substances (BAS) of these types of medicinal plant raw materials is practically not studied, therefore, its research is relevant. Aim. To study some BAS groups of the hydrophilic fraction of coriander fruits ( Coriandrum sativum L.) and fennel fruits ( Foeniculum vulgare Mill.) and their infusions. Materials and methods. Coriander fruits and fennel fruits were purchased from a pharmacy and met the requirements of the fifteenth edition of the State Pharmacopoeia of the Russian Federation. The fruit infusions were prepared according to the instructions on the packaging. The studies were conducted according to the methods of the fifteenth edition of the State Pharmacopoeia of the Russian Federation. Results and discussion. In fennel fruits ( Foeniculum vulgare Mill.), coriander fruits ( Coriandrum sativum L.), and infusions made from the fruits, the presence of tannins, flavonoids, polysaccharides, and free amino acids was confirmed, and their quantitative content was determined. It has been established that the content of hydrophilic fraction substances exceeds the content of essential oil in the raw material, but their amount in infusions prepared according to the instructions is low, and further research of the complex of bioactive substances in infusions of coriander and fennel fruits is required. Conclusion. The hydrophilic fraction of the fennel fruits and coriander fruits, as well as their infusions, have been studied, and the need for further in-depth research has been shown, with the search for marker compounds that determine the pharmacological activity of the aqueous extracts.