Can the Combination of White Blood Cell Count and C-Reactive Protein Rule Out Pediatric Appendicitis, a Retrospective Analysis?
The PA patients in our study had significantly higher inflammatory biomarkers than the non-PA patients. Combining WBC less than 10.0 k/mm<sup>3</sup> and CRP less than 1.0 mg/dL was 93.0% sensitive to rule out PA. Researchers should consider this combination of biomarkers to rule out PA in future prospective studies.
Authors
- Scott Gutovitz (ORCID: https://orcid.org/0000-0002-0931-5901)
- Sarah M. Stoner
- Sarah Kleist
- Jan W. Koper (ORCID: https://orcid.org/0009-0004-4269-532X)
Institutions
- Hamilton Medical Center (US)
Publication Details
- Journal
- HCA Healthcare Journal of Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.36518/2689-0216.2137
- Primary Topic
- Appendicitis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- HCA Healthcare