Nonglomerular Hypocomplementemic Interstitial Nephritis

We encountered a patient with interstitial nephritis and low complement level. The reason behind this rare phenomenon remains unclear in recent literature. As of 2024, only 11 other known cases of AIN have been found to have hypocomplementemia, making it a rare and curious pathophysiological process. More research and data are needed for further investigation into this exciting new pathology, its fundamental process, and potential treatment variations aside from those already used in AIN.