Comparison of protons and very high-energy electrons transmission pencil-beam-scanning for FLASH radiotherapy
The importance of treatment parameters (such as pulse repetition frequency) for VHEEs to reach ultra-high dose rates was assessed. With their high plan quality, VHEEs could constitute a viable alternative to proton transmission plans and a promising modality for FLASH therapy. The proposed FLASH index offers a robust tool to compare the FLASH potential across treatment modalities.
Authors
- Ludovic De Marzi (ORCID: https://orcid.org/0000-0001-8577-2381)
- Mateusz Sitarz (ORCID: https://orcid.org/0000-0001-6219-3256)
- Louis Ermeneux (ORCID: https://orcid.org/0009-0009-3209-3890)
- P. Lansonneur (ORCID: https://orcid.org/0009-0004-3615-8405)
- G. Créhange (ORCID: https://orcid.org/0000-0002-7127-9323)
- Pierre Loap (ORCID: https://orcid.org/0000-0001-8863-8110)
- Anthony Magliari (ORCID: https://orcid.org/0000-0002-3120-8053)
- Flavia Gesualdi (ORCID: https://orcid.org/0000-0002-4080-7840)
Institutions
- Inserm (FR)
- Université Paris Sciences et Lettres (FR)
- Hôpital Georges-Clemenceau (FR)
- Varian Medical Systems (United States) (US)
- Institut Curie (FR)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100860
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Agence Nationale de la Recherche
- Grand Équipement National De Calcul Intensif