A retrospective analysis of phase I and phase I/II investigator-initiated clinical trials conducted by the Swiss Group for Clinical Cancer Research (SAKK)

These findings highlight the safety profile, efficacy outcomes, and diversity of treatments in SAKK-conducted phase I trials, providing valuable insights into the investigator-initiated early clinical trials landscape in Switzerland.

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Publication Details

Journal
ESMO Open
Published
2025-10-29
DOI
https://doi.org/10.1016/j.esmoop.2025.105876
Primary Topic
Statistical Methods in Clinical Trials
Type
article
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article

A retrospective analysis of phase I and phase I/II investigator-initiated clinical trials conducted by the Swiss Group for Clinical Cancer Research (SAKK)

Simon Haefliger, Kira‐Lee Koster, Markus Joerger, Roger von Moos et al.
ESMO Open
Statistical Methods in Clinical Trials
article

A retrospective analysis of phase I and phase I/II investigator-initiated clinical trials conducted by the Swiss Group for Clinical Cancer Research (SAKK)

Simon Haefliger, Kira‐Lee Koster, Markus Joerger, Roger von Moos, Dagmar Hess, Ilaria Colombo, Martina Imbimbo, A. Rojas Mora, Anastasios Stathis, Krisztián Homicskó, Stefanie Hayoz, Klaus Eckhardt, Francesco Bertoni, Christian Britschgi, Cristiana Sessa
article en

Abstract

These findings highlight the safety profile, efficacy outcomes, and diversity of treatments in SAKK-conducted phase I trials, providing valuable insights into the investigator-initiated early clinical trials landscape in Switzerland.

ESMO OpenVol. 10(11)
University of Bern (CH), University of St.Gallen (CH), Kantonsspital St. Gallen (CH), University Hospital of Bern (CH), Swiss Paediatric Oncology Group (CH), Kantonsspital Winterthur (CH), Institute of Oncology Research (CH), Swiss Group For Clinical Cancer Research (CH), Kantonsspital Graubünden (CH)
Openalex Percentile: Top 70%
Statistical Methods in Clinical Trials
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