Effect of TGF-β1 transfected dental pulp derived mesenchymal stem cells on <i>ın vivo</i> cartilage regeneration.
TGF-β1 transfection enhances the chondrogenic potential of mesenchymal stem cells by stimulating reparative cellular mechanisms and promoting the formation of hyaline cartilage, thereby facilitating more effective tissue regeneration. These findings suggest that this strategy holds considerable potential for clinical application in cartilage repair and regeneration.
Authors
- Zeynep Burçin Gönen (ORCID: https://orcid.org/0000-0003-2725-9330)
- Ateş Kara (ORCID: https://orcid.org/0000-0002-1654-3232)
- Saim Özdamar (ORCID: https://orcid.org/0000-0003-4440-5360)
- Hasan Salkın (ORCID: https://orcid.org/0000-0001-9404-2348)
- Betul Tekin Alpargu
Institutions
- Pamukkale University (TR)
- Beykent University (TR)
- Erciyes University (TR)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.22038/ijbms.2025.87715.18946
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erciyes Üniversitesi