A Double Machine Learning Approach for Combining Experimental and Observational Studies

Abstract: Experimental and observational studies often lack validity due to untestable assumptions. We propose a double machine learning approach to combine experimental and observational studies, allowing practitioners to test for assumption violations and estimate treatment effects consistently. Our framework proposes a falsification test for external validity and ignorability under milder assumptions. We provide consistent treatment effect estimators even when one of the assumptions is violated. However, our no-free-lunch theorem highlights the necessity of accurately identifying the violated assumption for consistent treatment effect estimation. Through comparative analyses, we show our framework's superiority over existing data fusion methods. The practical utility of our approach is further exemplified by three real-world case studies, underscoring its potential for widespread application in empirical research.

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Publication Details

Journal
Observational Studies
Published
2025-01-01
DOI
https://doi.org/10.1353/obs.2025.a973068
Primary Topic
Advanced Causal Inference Techniques
Type
article
Field-Weighted Citation Impact
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article

A Double Machine Learning Approach for Combining Experimental and Observational Studies

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Observational Studies
Advanced Causal Inference Techniques
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A Double Machine Learning Approach for Combining Experimental and Observational Studies

Vittorio Orlandi, Cynthia Rudin, Marco Morucci, Alexander Volfovsky, Harsh Parikh, Sudeepa Roy
article en

Abstract

Abstract: Experimental and observational studies often lack validity due to untestable assumptions. We propose a double machine learning approach to combine experimental and observational studies, allowing practitioners to test for assumption violations and estimate treatment effects consistently. Our framework proposes a falsification test for external validity and ignorability under milder assumptions. We provide consistent treatment effect estimators even when one of the assumptions is violated. However, our no-free-lunch theorem highlights the necessity of accurately identifying the violated assumption for consistent treatment effect estimation. Through comparative analyses, we show our framework's superiority over existing data fusion methods. The practical utility of our approach is further exemplified by three real-world case studies, underscoring its potential for widespread application in empirical research.

Observational StudiesVol. 11(3)
Openalex Percentile: Top 70%
Advanced Causal Inference Techniques
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