Impact of Fasting on Granulocyte Chemotactic Protein-2 Chemokine and Lactate Dehydrogenase Enzyme Activity in the Development of Dental Caries

This study found that fasting impacts biomarkers related to dental health. Levels of GCP-2 and LDH exhibited considerable changes, whereas pH and salivary flow rate remained unchanged. Reduced GCP-2 levels during fasting may suggest a decrease in inflammatory activity, which in turn lowers the risk of periodontal disease. In addition, reducing LDH levels during fasting may lead to a dynamic interplay between metabolic states, oral health and tissue stress.