Systemic immunosuppression from ultraviolet radiation exposure inhibits cancer immunotherapy
Our data indicate that patients with melanoma and other cancers on immunotherapy should avoid repeated sun exposure.
Authors
- Isabella Mataloni
- Timothy Budden (ORCID: https://orcid.org/0000-0003-2500-2814)
- Sara Valpione (ORCID: https://orcid.org/0000-0001-9641-3819)
- Pedro Durao
- Graham M. Lord (ORCID: https://orcid.org/0000-0003-2069-4743)
- Karthik Mallela (ORCID: https://orcid.org/0000-0003-3330-955X)
- Shilpa Gurung (ORCID: https://orcid.org/0000-0003-1577-5880)
- Luke B. Roberts (ORCID: https://orcid.org/0000-0003-1143-304X)
- Adam Hurlstone
- Mirco Mastrangelo (ORCID: https://orcid.org/0000-0003-2232-7090)
- Antonia Banyard (ORCID: https://orcid.org/0000-0002-2430-8013)
- Amaya Virós (ORCID: https://orcid.org/0000-0001-5177-5015)
- Garry Ashton
- Martha Gutteridge
Institutions
- King's College London (GB)
- Salford Royal NHS Foundation Trust (GB)
- Cancer Research UK (GB)
- University of Manchester (GB)
- Cell and Gene Therapy Catapult (GB)
- Cancer Research UK Manchester Institute (GB)
- The Christie NHS Foundation Trust (GB)
- NIHR Manchester Biomedical Research Centre (GB)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1136/jitc-2025-012527
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancer Research UK