Childhood infections as predisposing factors to developing psoriasis vulgaris into early adulthood

We demonstrate, for the first time, the effect of exposure to infections during the first years of life and the subsequent development of psoriasis extending into early adulthood. Our study indicates that early exposure to infections may influence the development of the adaptive immune system during formative years. This modulation is evidenced by the higher incidence of psoriasis observed in early adulthood, several years after the initial exposure.

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Publication Details

Journal
British Journal of Dermatology
Published
2025-10-25
DOI
https://doi.org/10.1093/bjd/ljaf416
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
Field-Weighted Citation Impact
0.00
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article

Childhood infections as predisposing factors to developing psoriasis vulgaris into early adulthood

Debojyoti Das, Johnny Ludvigsson, Charlotta Enerbäck, Joana Thimjo
British Journal of Dermatology
Psoriasis: Treatment and Pathogenesis
article

Childhood infections as predisposing factors to developing psoriasis vulgaris into early adulthood

Debojyoti Das, Johnny Ludvigsson, Charlotta Enerbäck, Joana Thimjo
article en

Abstract

We demonstrate, for the first time, the effect of exposure to infections during the first years of life and the subsequent development of psoriasis extending into early adulthood. Our study indicates that early exposure to infections may influence the development of the adaptive immune system during formative years. This modulation is evidenced by the higher incidence of psoriasis observed in early adulthood, several years after the initial exposure.

British Journal of DermatologyVol. 194(3)
Linköping University (SE), Linköping University Hospital (SE)
Openalex Percentile: Top 67%
Psoriasis: Treatment and Pathogenesis
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