Chest-sited intraventricular access devices for cerliponase alfa infusion in Batten disease at a single tertiary United Kingdom pediatric center
Chest-sited intracerebroventricular access devices for cerliponase alfa infusions offered benefits that included reduced sedation, easier access, better device securing, higher access success rates, and greater nursing satisfaction. Both devices had similar survival rates and incident and complication rates. Chest-sited devices can be considered a safe and effective alternative in this setting.
Authors
- Bethany H. Brown
- Gary Kok Yew Chan (ORCID: https://orcid.org/0000-0002-5186-0479)
- Arunabha Ghosh (ORCID: https://orcid.org/0000-0002-8202-8693)
- Simon Jones (ORCID: https://orcid.org/0000-0002-5117-0566)
- Aimée Donald (ORCID: https://orcid.org/0000-0002-2623-5233)
- Dipak Ram (ORCID: https://orcid.org/0000-0001-8544-2534)
- Ian Kamaly-Asl (ORCID: https://orcid.org/0000-0003-1706-3887)
- Fiona Heap
- Jack Read
- Stephanie Rhead
- Lervia Acquaah
Institutions
- University of Exeter (GB)
- University of Manchester (GB)
- Royal Manchester Children's Hospital (GB)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3171/2025.7.peds25222
- Citations
- 1
- Primary Topic
- Lysosomal Storage Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16