Comparison of cone beam computed tomography post-processing methods for online adaptive proton therapy of prostate cancer
An advanced CBCT system enables proton dose calculations performed directly on the CBCT, demonstrating sufficient accuracy for integration into an OAPT workflow. Additional CBCT-based post-processing techniques are recommended to maximize the dosimetric benefit of plan adaptation in all patient populations.
Authors
- Daniel H. Bushe
- Brian Winey (ORCID: https://orcid.org/0000-0002-3894-3755)
- Nils Peters (ORCID: https://orcid.org/0000-0003-0860-5517)
- Harald Paganetti (ORCID: https://orcid.org/0000-0002-6257-2413)
- Hoyeon Lee (ORCID: https://orcid.org/0000-0002-1165-1509)
- Mislav Bobić (ORCID: https://orcid.org/0000-0002-9409-8680)
- Jason A. Efstathiou (ORCID: https://orcid.org/0000-0003-0996-0350)
- Lena Nenoff (ORCID: https://orcid.org/0000-0002-7468-835X)
- J. Pursley (ORCID: https://orcid.org/0000-0002-0531-6798)
Institutions
- Harvard University (US)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- ETH Zurich (CH)
- Massachusetts General Hospital (US)
- Fred Hutch Cancer Center (US)
- OncoRay (DE)
- University Hospital Carl Gustav Carus (DE)
Publication Details
- Journal
- Physics and Imaging in Radiation Oncology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.phro.2025.100858
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eidgenössische Technische Hochschule Zürich
- National Cancer Institute