Symptom Burden and Patient-Reported Outcomes in Kidney Transplant Recipients: Results From the TransplantLines Biobank and Cohort Studies
The most occurring symptoms were tiredness, bruises, and lack of energy, and the most distressing symptoms were menstrual problems, impotence, and joint pain. The strongest determinants of symptom burden were female sex, malnutrition, cyclosporine use, and proton pump inhibitor use. The associations of symptom burden with patient-related outcomes underline the importance of addressing symptom status after transplant.
Authors
- Henri G. D. Leuvenink (ORCID: https://orcid.org/0000-0001-5036-2999)
- António W. Gomes‐Neto (ORCID: https://orcid.org/0000-0002-4398-4877)
- C. Tji Gan (ORCID: https://orcid.org/0000-0002-1310-4189)
- Marius C. van den Heuvel (ORCID: https://orcid.org/0000-0001-6985-7107)
- Coby Annema (ORCID: https://orcid.org/0000-0001-8663-2145)
- Erik A.M. Verschuuren (ORCID: https://orcid.org/0000-0002-6807-6744)
- Daan J. Touw (ORCID: https://orcid.org/0000-0002-1429-4789)
- Bouke G. Hepkema (ORCID: https://orcid.org/0000-0002-3906-9887)
- J. Casper Swarte (ORCID: https://orcid.org/0000-0002-3709-9193)
- S.P. Berger
- Coretta van Leer‐Buter (ORCID: https://orcid.org/0000-0002-4072-7373)
- Eelko Hak (ORCID: https://orcid.org/0000-0003-0849-7210)
- Svea Nolte (ORCID: https://orcid.org/0000-0003-4742-1446)
- Rianne M. Douwes (ORCID: https://orcid.org/0000-0002-2517-5769)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Frank Klont (ORCID: https://orcid.org/0000-0003-3503-1694)
- M.F. Eisenga
- Stefan P. Berger (ORCID: https://orcid.org/0000-0003-2228-4676)
- Vincent Erwin de Meijer (ORCID: https://orcid.org/0000-0002-7900-5917)
- T.J. Knobbe
- Frank A.J.A. Bodewes (ORCID: https://orcid.org/0000-0003-0263-9791)
- Robert A. Pol (ORCID: https://orcid.org/0000-0002-2236-5233)
- H. Blokzijl
- Daan Kremer (ORCID: https://orcid.org/0000-0003-0011-115X)
- Michiel E. Erasmus (ORCID: https://orcid.org/0000-0002-6234-2976)
- H.G.M. Niesters
- Charlotte A. te Velde‐Keyzer (ORCID: https://orcid.org/0000-0002-8197-8056)
- Jan‐Stephan Sanders (ORCID: https://orcid.org/0000-0002-0904-3969)
- Riemer J H J A Slart
- Caecilia S E Doorenbos (ORCID: https://orcid.org/0000-0001-8036-520X)
- Jacqueline T. Jonker (ORCID: https://orcid.org/0009-0008-2698-8519)
- Michel J. Vos (ORCID: https://orcid.org/0000-0001-9379-2219)
- Gerard D. H. Dijkstra (ORCID: https://orcid.org/0000-0003-4563-7462)
- Tim J. Knobbe (ORCID: https://orcid.org/0000-0003-3246-3192)
- Niels L. Riemersma (ORCID: https://orcid.org/0000-0002-0203-7574)
- Adelita V. Ranchor (ORCID: https://orcid.org/0000-0001-7048-3771)
- Marco van Londen (ORCID: https://orcid.org/0000-0001-7145-3240)
- Martin H. de Borst (ORCID: https://orcid.org/0000-0002-4127-8733)
- Ute Bültmann (ORCID: https://orcid.org/0000-0001-9589-9220)
- Marion J. Siebelink (ORCID: https://orcid.org/0000-0001-5366-1732)
- Willem S. Lexmond
- R.K. Weersma
- Arjan Diepstra (ORCID: https://orcid.org/0000-0001-9239-1050)
- Michele F. Eisenga (ORCID: https://orcid.org/0000-0002-2484-6233)
- L. Joost van Pelt (ORCID: https://orcid.org/0000-0001-5538-1806)
- D. Kremer
- Gertrude J. Nieuwenhuis-Moeke
- Naser B.N. Shehab (ORCID: https://orcid.org/0000-0002-2663-6336)
- SJL Bakker
- Marieke T. de Boer (ORCID: https://orcid.org/0009-0008-0634-4740)
- Anna M Posthumus (ORCID: https://orcid.org/0009-0001-6520-6830)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1016/j.xkme.2025.101168
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00