POST-LOAD PLASMA GLUCOSE INCREASE (PG-GAP) AS A RISK FACTOR FOR DEVELOPING DYSGLYCEMIA IN PATIENTS WITH TRANSFUSION-DEPENDENT Β-THALASSEMIA (Β-TDT): RETROSPECTIVE ANALYSIS OVER 8 YEARS

The findings suggest that a high post-load plasma glucose gap (≥ 75<sup>th</sup> percentile or ≥ 30 mg/dL) is associated with a progressively increasing risk of glucose dysregulation over the next 6 to 8 years. These findings underscore the importance of a personalized approach to assessing the risk of early glucose metabolic disorders in β-TDT patients who are typically classified as normoglycemic.

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Journal
Mediterranean Journal of Hematology and Infectious Diseases
Published
2025-10-31
DOI
https://doi.org/10.4084/mjhid.2025.069
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
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article

POST-LOAD PLASMA GLUCOSE INCREASE (PG-GAP) AS A RISK FACTOR FOR DEVELOPING DYSGLYCEMIA IN PATIENTS WITH TRANSFUSION-DEPENDENT Β-THALASSEMIA (Β-TDT): RETROSPECTIVE ANALYSIS OVER 8 YEARS

Ploutarchos Tzoulis, Mohammad Faranoush, Theodora Maria Venou, Shahina Daar et al.
Mediterranean Journal of Hematology and Infectious Diseases
Hemoglobinopathies and Related Disorders
article

POST-LOAD PLASMA GLUCOSE INCREASE (PG-GAP) AS A RISK FACTOR FOR DEVELOPING DYSGLYCEMIA IN PATIENTS WITH TRANSFUSION-DEPENDENT Β-THALASSEMIA (Β-TDT): RETROSPECTIVE ANALYSIS OVER 8 YEARS

Ploutarchos Tzoulis, Mohammad Faranoush, Theodora Maria Venou, Shahina Daar, Ashraf Tawfik Soliman, Efthymia Vlachaki, Christos Kattamis, Vincenzo De Sanctis
article en

Abstract

The findings suggest that a high post-load plasma glucose gap (≥ 75<sup>th</sup> percentile or ≥ 30 mg/dL) is associated with a progressively increasing risk of glucose dysregulation over the next 6 to 8 years. These findings underscore the importance of a personalized approach to assessing the risk of early glucose metabolic disorders in β-TDT patients who are typically classified as normoglycemic.

Mediterranean Journal of Hematology and Infectious DiseasesVol. 17(1)
Iran University of Medical Sciences (IR), Whittington Hospital (GB), Hamad General Hospital (QA), University College London (GB), Sultan Qaboos University (OM)
Openalex Percentile: Top 56%
Hemoglobinopathies and Related Disorders
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