Diagnostic potential of allergen-specific lymphocyte stimulation test in hen’s egg yolk–induced, food protein–induced enterocolitis syndrome
The EY/EW lymphocyte response ratio may serve as a supportive diagnostic biomarker for EY-FPIES. Despite its limited sensitivity, the high specificity and positive predictive value suggest that ALST could help reduce reliance on invasive oral food challenges in clinical practice.
Authors
- Tadashi Matsuda (ORCID: https://orcid.org/0000-0003-0973-1478)
- Takafumi Takase
- Hisashi Nishimori
- Ryo Imakiire (ORCID: https://orcid.org/0000-0001-8799-9408)
- Shingo Yamada (ORCID: https://orcid.org/0000-0001-9250-6241)
- Tomoyuki Arima (ORCID: https://orcid.org/0000-0002-5460-9861)
- Kana Hamada (ORCID: https://orcid.org/0000-0003-2182-9822)
- Takahiro Nishida (ORCID: https://orcid.org/0000-0001-8791-8620)
- Hiroyuki Hirai (ORCID: https://orcid.org/0000-0001-7302-7587)
- Fumiko Iwai
- Kayoko Matsuo (ORCID: https://orcid.org/0000-0002-5902-1629)
- Chiho Tatsumoto
- Reiko Tokuda
- Makiko Nakamoto
- Mizuho Nagao (ORCID: https://orcid.org/0000-0003-3557-8761)
- Takao Fujisawa (ORCID: https://orcid.org/0000-0002-9196-9436)
- Keigo Kainuma (ORCID: https://orcid.org/0000-0002-9036-5550)
- Rei Kanai
- Ryuji Yasui
Institutions
- Kagoshima University (JP)
- Yokkaichi University (JP)
- Kagawa University (JP)
- Tokuda Hospital (BG)
- Nemours Children’s Clinic (US)
- Atlanta Allergy and Asthma Clinic (US)
- Kobe Children's Hospital (JP)
- Mie Chuo Medical Center (JP)
- National Mie Hospital (JP)
- Imakiire General Hospital (JP)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-10-31
- DOI
- https://doi.org/10.1016/j.jacig.2025.100596
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00