Multidisciplinary Management in the Diabetes Reversal Clinic Promotes Diabetes Remission

Background/Objective: To investigate the remission rate and metabolic outcomes under the Diabetes Reversal Clinic with multidisciplinary management.Methods: Patients with type 2 diabetes who visited the Diabetes Reversal Clinic from April 2022 to December 2024 were enrolled.Baseline characteristics and metabolic indicators were recorded.Participants received comprehensive multidisciplinary management including personalized treatment plans, structured lifestyle modification, continuous glucose monitoring, and traditional Chinese medicine as adjunctive therapy.After 6months, the remission rate, the rate of target glycated hemoglobin A1c <53 mmol/mol (7.0%), and changes of metabolic indicators in patients were analyzed.Results: Our major results found that, among 171 patients with type 2 diabetes who were followed for more than 6 months, 50 (29.24%)patients achieved remission, and 149 (87.13%) patients achieved the target of glycated hemoglobin A1c <53 mmol/mol (7.0%).At the end of 2022, 2023 and 2024, the annual diabetes remission rate reached 6.12% (6/98), 16.78% (25/149), and 16.24% (19/117), respectively.The multidisciplinary management significantly decreased body mass index, waist circumference, waist-toheight ratio, fasting blood glucose, glycated hemoglobin A1c and homeostasis model assessment of insulin resistance, while significantly increased high-density lipoprotein cholesterol (all P<0.05).Conclusion: A diabetes remission rate of 29.24% and a target rate of 87.13% were obtained after 6 months of multidisciplinary management among patients with type 2 diabetes in the Diabetes Reversal Clinic.Our findings suggest that the multidisciplinary management model employed in the Diabetes Reversal Clinic is superior to conventional management in general outpatient clinics for promoting diabetes remission and metabolic reversal.