Volumetric Differences of Thalamic Nuclei Are Associated With Posttrauma Psychopathology
Whole thalamus volume and volumes of the sensorimotor and limbic thalamus may play an important role in the development of PTSD and MDD in the aftermath of trauma exposure. The interaction between PTSD and MDD symptoms and contrasting effects across PTSD symptom clusters and types of childhood adversity suggest that multiple neurobiological mechanisms are involved in shaping thalamic volume posttrauma.
Authors
- Laura Nawijn (ORCID: https://orcid.org/0000-0001-7183-8933)
- Orren Ravid
- Ryan J. Herringa (ORCID: https://orcid.org/0000-0002-1936-7959)
- Anna R. Hudson (ORCID: https://orcid.org/0000-0002-5752-7888)
- Wissam El‐Hage (ORCID: https://orcid.org/0000-0003-3877-0855)
- Jessie L. Frijling (ORCID: https://orcid.org/0000-0002-5055-340X)
- Negar Fani (ORCID: https://orcid.org/0000-0002-7720-252X)
- Shmuel Lissek (ORCID: https://orcid.org/0000-0001-7384-371X)
- Tanja Jovanović (ORCID: https://orcid.org/0000-0002-6456-0053)
- Yuval Neria (ORCID: https://orcid.org/0000-0001-5223-4333)
- Jacklynn M. Fitzgerald (ORCID: https://orcid.org/0000-0002-6076-4067)
- Robert R. J. M. Vermeiren (ORCID: https://orcid.org/0000-0002-8673-2207)
- Marisa Ross (ORCID: https://orcid.org/0000-0002-7769-5029)
- Emily L. Dennis (ORCID: https://orcid.org/0000-0001-7112-4009)
- Neda Jahanshad (ORCID: https://orcid.org/0000-0003-4401-8950)
- Scott McGill Nelson (ORCID: https://orcid.org/0000-0002-9099-3047)
- Mirjam van Zuiden (ORCID: https://orcid.org/0000-0002-1225-2702)
- Kerry Ressler
- Gopalkumar Rakesh (ORCID: https://orcid.org/0000-0002-7134-2804)
- Saskia B.J. Koch (ORCID: https://orcid.org/0000-0002-3628-6712)
- Adi Maron‐Katz (ORCID: https://orcid.org/0000-0003-4246-1748)
- Dick J. Veltman (ORCID: https://orcid.org/0000-0001-8971-4250)
- Courtney C. Haswell (ORCID: https://orcid.org/0000-0003-0562-9855)
- Anika Sierk (ORCID: https://orcid.org/0000-0002-1396-8075)
- Scott R. Sponheim (ORCID: https://orcid.org/0000-0002-2782-0856)
- Amit Lazarov (ORCID: https://orcid.org/0000-0002-2811-2739)
- Christine Larson (ORCID: https://orcid.org/0000-0001-7331-0817)
- Andrew S. Cotton (ORCID: https://orcid.org/0000-0002-4787-4528)
- David F. Tate (ORCID: https://orcid.org/0000-0003-0213-1920)
- Kelly Sambrook
- Richard J. Davidson (ORCID: https://orcid.org/0000-0002-8506-4964)
- Yann Quidé (ORCID: https://orcid.org/0000-0002-8569-7139)
- C. Lexi Baird
- Hannah Berg
- Benjamin Suarez‐Jimenez (ORCID: https://orcid.org/0000-0002-4765-2458)
- Antje Manthey
- Matthew Peverill (ORCID: https://orcid.org/0000-0002-8257-1004)
- Mike Angstadt (ORCID: https://orcid.org/0000-0003-4870-7649)
- Terri A. deRoon‐Cassini (ORCID: https://orcid.org/0000-0002-9485-0625)
- Ruth A. Lanius
- Evan M. Gordon (ORCID: https://orcid.org/0000-0002-2276-5237)
- Chadi G. Abdallah (ORCID: https://orcid.org/0000-0001-5783-6181)
- Ahmed Hussain (ORCID: https://orcid.org/0009-0005-8761-7525)
- Richard W. J. Neufeld (ORCID: https://orcid.org/0000-0002-3214-8603)
- Xin Wang (ORCID: https://orcid.org/0000-0001-6292-3087)
- Maria Densmore
- Guangming Lu (ORCID: https://orcid.org/0000-0003-4913-2314)
- Delin Sun (ORCID: https://orcid.org/0000-0003-3283-423X)
- Josh M. Cisler (ORCID: https://orcid.org/0000-0001-8257-7716)
- Jean Théberge (ORCID: https://orcid.org/0000-0001-7578-4469)
- Amit Etkin (ORCID: https://orcid.org/0000-0001-8259-3521)
- William C. Walker (ORCID: https://orcid.org/0000-0001-5813-3939)
- Judith K. Daniels (ORCID: https://orcid.org/0000-0001-6304-2310)
- Israel Liberzon (ORCID: https://orcid.org/0000-0002-4990-556X)
- Sanne J.H. van Rooij (ORCID: https://orcid.org/0000-0002-0160-7248)
- Nicholas D. Davenport (ORCID: https://orcid.org/0000-0002-3441-7256)
- Anthony King (ORCID: https://orcid.org/0000-0002-8131-396X)
- Daniel W. Grupe (ORCID: https://orcid.org/0000-0003-4927-7572)
- Elisabeth A. Wilde (ORCID: https://orcid.org/0000-0002-9839-4428)
- Jack B. Nitschke
- Bunmi O. Olatunji (ORCID: https://orcid.org/0000-0002-3573-4165)
- Sigal Zilcha‐Mano (ORCID: https://orcid.org/0000-0002-5645-4429)
- Jennifer Stevens (ORCID: https://orcid.org/0000-0001-6640-8592)
- Nick Steele (ORCID: https://orcid.org/0009-0004-2308-163X)
- Miranda Olff (ORCID: https://orcid.org/0000-0003-1016-9515)
- David X. Cifu (ORCID: https://orcid.org/0000-0003-1600-9387)
- Seth G. Disner (ORCID: https://orcid.org/0000-0003-3635-9421)
- Leonel Rangel-Jimenez
- Gen Li (ORCID: https://orcid.org/0000-0002-6883-2407)
- Hong Xie (ORCID: https://orcid.org/0000-0002-9165-8515)
- Paul M. Thompson (ORCID: https://orcid.org/0000-0002-4720-8867)
- Xi Zhu (ORCID: https://orcid.org/0000-0002-2634-2901)
- Erin N. O’Leary (ORCID: https://orcid.org/0000-0002-2993-7003)
- Henrik Walter
- Rajendra A. Morey
- Jennifer Urbano Blackford
- Carissa W Tomas
- Geoffrey May
- Li Wang (ORCID: https://orcid.org/0000-0002-0496-9500)
- Ye Zhu
Institutions
- Marquette University (US)
- Université de Tours (FR)
- Northwestern University (US)
- University of Southern California (US)
- Texas A&M Health Science Center (US)
- Western University (CA)
- Netherlands Institute for Neuroscience (NL)
- University of Minnesota (US)
- Nebraska Medical Center (US)
- Central European Institute of Technology (CZ)
- University of Wisconsin–Madison (US)
- University of Kentucky (US)
- Radboud University Nijmegen (NL)
- Emory University (US)
- Inserm (FR)
- Baylor University (US)
- Tel Aviv University (IL)
- University of Groningen (NL)
- Duke University (US)
- Virginia Commonwealth University (US)
- Wayne State University (US)
- Vanderbilt University (US)
- University of Washington (US)
- Medical College of Wisconsin (US)
- Washington University in St. Louis (US)
- VA Palo Alto Health Care System (US)
- University of Utah (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Leiden University Medical Center (NL)
- McLean Hospital (US)
- Ghent University Hospital (BE)
- Hunter Holmes McGuire VA Medical Center (US)
- University of Rochester Medical Center (US)
- New York Psychoanalytic Society and Institute (US)
- Arq Psychotrauma Expert Group (NL)
- Centre Hospitalier Universitaire de Tours (FR)
- Clinical Investigation Center Plurithematic Tours (FR)
- National Center for PTSD (US)
- Texas A&M Health Science Center (US)
- Amsterdam Neuroscience (NL)
- Minneapolis VA Health Care System (US)
- University of Wisconsin Health (US)
- Durham VA Medical Center (US)
- Duke University Hospital (US)
- Center for Occupational Research and Development (US)
- National Center for Post Traumatic Stress Disorder (US)
- George E. Wahlen Department of VA Medical Center (US)
- University of Chinese Academy of Sciences (CN)
- Imaging Center (US)
- University of Wisconsin–Milwaukee (US)
- New York State Psychiatric Institute
- University of Nebraska Medical Center (US)
- Charité - Universitätsmedizin Berlin (DE)
- Nanjing Medical University (CN)
- Neuroscience Research Australia (AU)
- The University of Texas at Austin (US)
- Nanjing University (CN)
- University of Amsterdam (NL)
- University of Toledo (US)
- Texas A&M University (US)
- University of Haifa (IL)
- Bryan College (US)
- Stanford University (US)
Publication Details
- Journal
- Biological Psychiatry Cognitive Neuroscience and Neuroimaging
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.bpsc.2025.10.016
- Primary Topic
- Posttraumatic Stress Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00