Tandem Reaction of Carbonyl Compounds with Triethylphosphite and Phenols: A Direct and Accessible Pathway to the Synthesis of the Benzo[d][1,2]oxaphosphole Derivatives
A new approach was proposed for the synthesis of the 3H-benzo[d][1,2]oxaphospholes ethyl esters by the three-component acid-catalyzed reaction of triethylphosphite with carbonyl compounds and phenols. It allows obtaining target structures in one synthetic step from available reagents. Trifluoromethanesulfonic acid was shown to be an effective catalyst for the process.
Authors
- В. Ф. Миронов (ORCID: https://orcid.org/0000-0002-4198-3774)
- D. A. Tatarinov (ORCID: https://orcid.org/0000-0002-9960-7499)
- Khasan R. Khayarov (ORCID: https://orcid.org/0000-0003-2913-5120)
- Makar A. Zaborsky (ORCID: https://orcid.org/0009-0007-0785-418X)
- Olga B. Babaeva (ORCID: https://orcid.org/0000-0001-8567-9873)
Institutions
- Kazan Federal University (RU)
- A.E. Arbuzov Institute of Organic and Physical Chemistry (RU)
Publication Details
- Journal
- Russian Journal of General Chemistry
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1134/s1070363225604867
- Primary Topic
- Organophosphorus compounds synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00