Exogenous carbon monoxide prevents a decrease of mitochondrial membrane potential in lipopolysaccharide-stimulated platelets

These results suggest that CO prevents a decrease in the platelet ΔΨm and thereby inhibits platelet activation by LPS treatment.

Authors

Masahiro Itoh (ORCID: https://orcid.org/0000-0002-6106-2761)
Hidenobu Miyaso (ORCID: https://orcid.org/0000-0003-2212-1500)
Yutaro Natsuyama (ORCID: https://orcid.org/0000-0003-3395-4364)
Shinichi Kawata (ORCID: https://orcid.org/0000-0002-9433-5682)
Tomiko Yakura (ORCID: https://orcid.org/0000-0002-2605-8396)
Zhong‐Lian Li (ORCID: https://orcid.org/0000-0002-2640-0518)
Miyuki Kuramasu
Eri Nanizawa (ORCID: https://orcid.org/0000-0002-6190-7875)
Munekazu Naito

Institutions

Tokyo Medical University (JP)
Aichi Medical University (JP)

Publication Details

Journal: The Journal of Toxicological Sciences
Published: 2025-01-01
DOI: https://doi.org/10.2131/jts.50.617
Primary Topic: Heme Oxygenase-1 and Carbon Monoxide
Type: article
Field-Weighted Citation Impact: 0.00

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article

Exogenous carbon monoxide prevents a decrease of mitochondrial membrane potential in lipopolysaccharide-stimulated platelets

Masahiro Itoh, Hidenobu Miyaso, Yutaro Natsuyama, Shinichi Kawata et al.

Jan 1, 2025

The Journal of Toxicological Sciences

Heme Oxygenase-1 and Carbon Monoxide

article

Exogenous carbon monoxide prevents a decrease of mitochondrial membrane potential in lipopolysaccharide-stimulated platelets

Masahiro Itoh, Hidenobu Miyaso, Yutaro Natsuyama, Shinichi Kawata, Tomiko Yakura, Zhong‐Lian Li, Miyuki Kuramasu, Eri Nanizawa, Munekazu Naito

January 1, 2025article en

Abstract

These results suggest that CO prevents a decrease in the platelet ΔΨm and thereby inhibits platelet activation by LPS treatment.

The Journal of Toxicological SciencesVol. 50(11)

Tokyo Medical University (JP), Aichi Medical University (JP)

Openalex Percentile: Top 72%

Heme Oxygenase-1 and Carbon Monoxide

DOI Open Access PDF OpenAlex

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Exogenous carbon monoxide prevents a decrease of mitochondrial membrane potential in lipopolysaccharide-stimulated platelets — Masahiro Itoh, Hidenobu Miyaso, et al. · The Journal of Toxicological Sciences (2025) | TGRS Research Map | TGRS